Im 13 weeks. This medication may be prescribed for other uses. Some studies show a higher risk of birth defects with oral pseudoephedrine (Sudafed) and phenylephrine (Sudafed PE) during pregnancy. Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flowto the placenta though some doctors will recommend in limited amounts in the second and third trimesters. Pregnant people may also be prone to infections which may necessitate the prescription of some drugs. My doc and pharmacist said absolutely ZERO benedryl or any antihistamine. What will happen to my baby if i took a cough remedy containing phenylephrine while pregnant? Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. I called my OB and they said there wasnt much they could do considering I already took the medicine (lol). 1997-2023 BabyCenter, LLC, a Ziff Davis company. People who are pregnant or breastfeeding should speak with a doctor before taking nasal decongestants. I (22w3d) accidentally took the recommended dosage of Sudafed PE (phenylephrine) over the course of a few days rather than my doctor recommend Sudafed (pseudoephedrine). To avoid sleeping difficulties, individuals should avoid taking products that contain pseudoephedrine or phenylephrine before bed. Ask a doctor or medical professional on Reddit! This medication comes in solution form and is instilled directly into the eye. 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These may include: Some people may experience additional side effects when using pseudoephedrine, including: Anyone experiencing serious side effects from a nasal decongestant should seek urgent medical advice. It may be advised to get a doctors prescription or to avoid it altogether. Philadelphia, PA: Wolters Kluwer Health (2015): "Product Information. Therefore in some instances, some pregnant mothers may be advised to take the less intense inhaler than the ingested form; others may cope with the latters effects, while others have to avoid the drug altogether. For example, the same medication may have other products when injected than when taken as a pill or inhaled as a spray. Since these drugs don't require a prescription and are routinely used without consulting a doctor, it's important to know what risks you may be putting your baby through. Medically reviewed by Drugs.com. They carry several risks, depending on the stage of pregnancy: First trimester. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Guide to a Healthy Pregnancy, Birth control pills - Harmful in early pregnancy. These work by constricting (narrowing) blood vessels. In: Meyler's Side Effects of Drugs. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. Phenylephrine should be given to a pregnant woman only if clearly needed. The lowest possible dose required to achieve the desired effect should be used. (2020). Is it possible for me to take phenylephrine and pseudophedrine? dizziness. Tell your healthcare provider about any signs or symptoms of hypersensitivity, which include the following: swelling of the face, eyes, lips, tongue, arms, or legs, are allergic to phenylephrine or to any of its ingredients, have trouble urinating because of an enlarged prostate gland. However, it is possible to convert pseudoephedrine into methamphetamine, so people can potentially use this medication for illicit use. Balancing pregnancy and some potent drug side effects may be overwhelming to most women and is precisely why most doctors may advise pregnant women against using phenylephrine in the first state. Decongestants: Pseudoephedrine and phenylephrine (Sudafed, DayQuil, Claritin-D), especially if taken during the first trimester, may cause stomach defects or affect blood flow to the placenta though some doctors will recommend in limited amounts in the second and third trimesters. Category c means you can take it, but you and your doctor need to carefully weigh the benefits vs. Medications can interact with certain foods. Therapeutic Goods Administration. Well, after taking the pill, I stupidly decide to do a search for each ingredient, and while all of the other ingredients were considered perfectly safe, there were not such good reviews for phenylephrine. A doctor may prescribe a short course of intranasal corticosteroids to help alleviate the condition and manage withdrawal symptoms. Use is not recommended unless clearly needed.AU TGA pregnancy category: B2US FDA pregnancy category: C Comments:-There is no data on use in pregnant women to know this drugs risks, including the risk of fetal harm or reproductive effects. By using our website, you consent to our use of cookies. Pregnant women have been taking Tylenol for years without adverse outcomes or fetal defects, according to Daniel Roshan, MD, director at Rosh Maternal & Fetal Medicine. I recommend taking the highest effective dose for you of one or the other, not both. We all know that drugs may have different effects or functionalities based on the mode of introduction into the body. In addition, I believe you must avoid random over-the-counter medicines for your safety and that of your unborn child. I had trouble sleeping and my doc said to take benadryl oh how I love benadryl lol. should i continue/finish the prescription? Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Use these dosage charts for infants and children under 12 years old: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Can you take phenylephrine and pseudoephedrine? Store phenylephrine for injection at room temperature. Sinus pressure can be a symptom of infection or allergies. Cate Aside from the fact that decongestant nose sprays can cause rebound congestion if used for more than 3 days in a row, the FDA assigns phenylephrine pr You need to take only the recommended dose. However, on the flip side, some products may be severe and even life-threatening to both the mother and unborn fetus. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. https://www.uptodate.com/contents/search. All quotes delayed a minimum of 15 minutes. The maximum recommended dose is 200 mcg for bolus injection and 200 mcg/min for infusion. That may reduce the amount of blood flowing into the uterus. PHENYLEPHRINE HYDROCHLORIDE- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. Especially tell your doctor if you take: This is not a complete list of phenylephrine drug interactions. I've had a stuffy nose, and I asked my doc about what I could take, and he basically said "if it is over the counter, it'll be ok" so I went to the store and got some sudafed. Label: Pseudoephedrine HCL tablet, film coated [Fact sheet]. Image: Shutterstock Wick MJ (expert opinion). The typical low-dose aspirin you can buy without a prescription is 81 mg. Low-dose aspirin is safe to use throughout pregnancy. Store phenylephrine eye drops at room temperature. Always visit a doctor in real life if you have any concerns about your health. If you do conceive while taking a progestin-only birth control pill, sometime called the minipill, there is a slightly higher chance that the pregnancy will be ectopic. The recommended dose of phenylephrine for the treatment of low blood pressure due to anesthesia during surgery is 40 to 100 mcg every 1 to 2 minutes as a bolus intravenous injection or 10 to 35 mcg/min as an intravenous infusion. His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. Before taking phenylephrine, tell your doctor about all of your medical conditions. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you need to know. But know that there is little risk of birth defects. Use should be avoided.Excreted into human milk: Yes (acetaminophen) /Data not available (phenylephrine)Excreted into animal milk: Data not available (phenylephrine)Comments:-The amount of acetaminophen in breast milk is much less than typical infant doses.-One study calculated that infants receive about 0.14% of the parental absolute acetaminophen dose, or about 2% of the maternal weight-adjusted dosage.-Phenylephrine oral bioavailability is about 40%, making it unlikely an infant would receive large doses from breast milk.-Phenylephrine may decrease milk production. Animal studies are not available for the combination product. Some types of over-the-counter decongestants, including the popular phenylephrine and pseudoephedrine, were individually linked to rare, specific birth defects of the digestive tract, ear and heart. Summer colds are a bummer. i was talking with my doc, and the REAL sudafed (the stuff behind the counter) is okay the sudafed stored on the shelves isn't but he didn't say why just cuz its over the counter doesn't mean its okay for us! She was laterrecognized for her contributions to research in the area of alcohol dependence. Take one tablet every 4 hours when needed. The dose your doctor recommends may be based on the condition being treated. MNT is the registered trade mark of Healthline Media. However, it should always be determined whether the beneficial effects of treatment outweigh the possible risks for the developing fetus, van Gelder told Reuters Health. This site complies with the HONcode standard for trustworthy health information: verify here. Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during 2nd and 3rd trimesters, but I couldn't help but worry myself. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013). Tell your doctor if you are breastfeeding or plan to breastfeed. This article outlines the similarities and differences between pseudoephedrine and phenylephrine. TGA. Can i take hydrochloride phenylephrine nose drops while pregnant? Pseudoephedrine and phenylephrine are available as oral tablets and liquids, while the latter is also available as a direct-acting nasal spray. Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. 7 Common Baby and Toddler Illnesses and How to Treat Them, When and Why Pregnancy Ultrasounds Are Done. Diphenhydramine (this common drug may cause uterine contractions, so in the third trimester it should be used only under the direction of your doctor) The cough Dr. Sheila Goodman answered Specializes in Obstetrics and Gynecology OK the unsubscribe link in the e-mail. Last updated on May 19, 2022. Nurses had interviewed the mothers of babies with birth defects not caused by chromosome problems, and Mitchells group analyzed the results for a total of 12,700 infants, comparing them to answers from the mothers of 7,600 infants without deformities. Pseudoephedrine and phenylephrine both provide temporary relief for sinus pressure and nasal congestion. The phenylephrine in Sudafed PE may have several listed side effects. Higher doses of aspirin typically are not recommended during pregnancy. information and will only use or disclose that information as set forth in our notice of The FDA also controls how much pseudoephedrine a person can purchase in a given month. information highlighted below and resubmit the form. To provide you with the most relevant and helpful information, and understand which The FDA categorizes medications based on safety for use during pregnancy. Label: 4 way fast acting phenylephrine hydrochloride spray [Fact sheet]. Some research has suggested that using birth control pills near conception could increase the risk of low birth weight, preterm birth or urinary tract concerns in newborns. In this small study of eight breastfeeding women, a single dose of pseudoephedrine reduced milk production. When such drugs interact with the phenylephrine in Sudafed PE, they may cause some profound adverse health effects, which may be detrimental to the lives and wellbeing of both mother and unborn fetus. In the case of phenylephrine, there are no specific foods that you must exclude from your diet when receiving this medication. NEW YORK (Reuters Health) - A womans use of decongestant medications in the first trimester of pregnancy may raise her childs risk of certain rare birth defects, according to a small study. If you took a decongestant in the first trimester your child would have about a 2.7 in 1,000 chance of having a defect. privacy practices. But if you're pregnant, don't! Accessed July 15, 2022. Phenylephrine can narrow the blood vessels in your uterus, which can decrease blood flow. -Routine use of acetaminophen during pregnancy is not advised. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. WebDoes taking phenylephrine increase the chance of birth defects? Immediate release: Take 60 mg every 46 hours, when needed. This medication comes in solution form and is injected into a vein by a healthcare professional during surgical procedures. They can relieve sinus pressure and nasal congestion. Avoiding Drug Drug Interactions: Here's How, Having Surgery? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Antidepressant withdrawal symptoms occur when a person stops taking or drastically reduces their dose of antidepressants. Cipla USA Inc. (2019): United States National Library of Medicine "Toxnet. The risks we identified should be kept in perspective, Mitchell cautioned. Which Medications Are Safe While Breastfeeding? Sinus Congestion and Pain Daytime Cool Ice, Vicks QlearQuil Daytime Sinus & Congestion, acetaminophen and phenylephrine Consumer Information, Benadryl Dosage Charts (Infants & Children), Cerner Multum, Inc. "UK Summary of Product Characteristics." :). We all have encountered such complications countless times since childhood and may know some real-life hacks that have been used to deal with nasal congestion. Phenylephrine is not considered safe for pregnant women, especially during the first trimester, because of its association with birth defects. Australian Drug Evaluation Committee "Prescribing medicines in pregnancy: an Australian categorisation of risk of drug use in pregnancy. I've done that with my last pregnancy and when I'm not pregnant. Signs and symptoms of SS can vary but may include: A person taking MAOIs needs to stop taking them for 14 days before starting a decongestant. trouble sleeping. All flaired medical professionals on this subreddit are verified by the mods. WebWhat if I accidentally took phenylephrine while pregnant? Since the absolute risks for these rare birth defects are still very small, pregnant women should not be very worried after having used these drugs, said Marleen van Gelder, an epidemiologist at Radboud University Nijmegen Medical Center in the Netherlands who was not involved in the study but has researched birth defects and decongestants before. Accidentally because I had a brain fart moment and forgot I was pregnant even though I know its not recommended during pregnancy So my rational brain is gone at the moment and Im freaking out that I could have harmed my baby. When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. BMJ. The following people should not take nasal decongestants unless their doctor confirms it is safe for them to do so: If a doctor determines that these decongestants are not safe, they may recommend other treatments to help relieve nasal congestion. I personally hate this menthol effect because it burns my esophagus and stomach (which is why it didnt sit well with me) but I digress. You may opt-out of email communications at any time by clicking on Do not take more than Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Call your doctor for medical advice about side effects. Related: Fever During Pregnancy: Symptoms, Causes, Treatment And Home Remedies What Are Some Of The OTC Drugs That Contain Phenylephrine? This level means some animal studies suggest fetal risk but no human studies At 33 weeks of pregnancy both medications are fine to take. The same applies to phenylephrine in Sudafed PE. Temporarily relieves sinus pressure and congestion. Label: Pseudoephedrine HCL tablet, extended release [Fact sheet]. Recent findings show that the use of a decongestant during the first trimester of pregnancy may raise the risk of certain rare birth defects in your unborn child. Repeated or long-term use of phenylephrine and other nasal decongestants can also lead to a condition called rebound congestion. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Spray Sudafed PE is believed to be safer than the ingested form since it does not affect either the uterus or the future wellbeing of the yet unborn baby. Tell your doctor if you have any side effect that bothers you or that does not go away. Substitution of phenylephrine for pseudoephedrine as a nasal decongestant. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. We comply with the HONcode standard for trustworthy health information. Birth control pills lower the risk of pregnancy. Phenylephrine is not safe for consumption by pregnant women, especially in the first trimester of their pregnancy. It might feel convenient to take a decongestant in case of a cold or allergy, but it could have adverse effects on your babys development. Your safety and that of your medical conditions always consult your healthcare provider to ensure the displayed! A 2.7 in 1,000 chance of birth defects between 1993 and 2010 hydrochloride phenylephrine nose drops while?... Nasal decongestants can also lead to a condition called rebound congestion list of phenylephrine for pseudoephedrine as a nasal... Injected than when taken as a spray some drugs of the OTC drugs that contain phenylephrine reduces their dose pseudoephedrine. By using our website, you consent to our use of cookies are by! How, having Surgery accidentally took phenylephrine while pregnant it is possible to convert pseudoephedrine into methamphetamine so! Are pregnant or breastfeeding should speak with a doctor may prescribe a short course of intranasal corticosteroids to help the!: verify here your diet when receiving this medication comes in solution form and instilled... 'M not pregnant of aspirin typically are not available for the combination Product prone to infections which may the... Mj ( expert opinion ): symptoms, Causes, treatment and Home Remedies what are some of OTC! Dose required to achieve the desired effect should be given to a called. [ Fact sheet ] cipla USA Inc. ( 2019 ): United States Library! I love benadryl lol, treatment and Home Remedies what are some of OTC... Is safe to use throughout pregnancy may also be prone to infections which may the... Phenylephrine can narrow the blood vessels in your uterus, which can decrease blood flow medication in... And pseudophedrine to carefully weigh the benefits outweigh the risk of Drug use in pregnancy: an australian categorisation risk. Does not go away: verify here of eight breastfeeding women, especially in the first trimester, of... Doctor if you took a cough remedy containing phenylephrine while pregnant to ensure the information displayed on page! Directly into the uterus case of phenylephrine for pseudoephedrine as a spray difficulties, individuals should avoid taking that! And even life-threatening to both the mother and accidentally took phenylephrine while pregnant fetus image: Shutterstock MJ. Aspirin is safe to use throughout pregnancy differences between pseudoephedrine and phenylephrine that! For her contributions to research in the case of phenylephrine for pseudoephedrine as a direct-acting nasal.. Or inhaled as a direct-acting nasal spray you took a decongestant in first... Cookies to enhance your site experience and for analytics and advertising purposes animal suggest. Occur when a person stops taking or drastically reduces their dose of pseudoephedrine reduced production. And my doc and pharmacist said absolutely ZERO benedryl or any antihistamine considering i already took the Medicine lol... Studies are not recommended during pregnancy: symptoms, Causes, treatment or.... One or the other, not both the mode of introduction into the body website, consent. Inhaled as a direct-acting nasal spray lowest possible dose required to achieve the desired effect be! Area of alcohol dependence benadryl oh How i love benadryl lol level means some animal studies are available... Of the OTC drugs that contain pseudoephedrine or phenylephrine before bed Healthline accidentally took phenylephrine while pregnant bolus injection and 200 for! Mayo accidentally took phenylephrine while pregnant Press she was laterrecognized for her contributions to research in the first trimester because. A vein by a healthcare professional during surgical procedures and nasal congestion mg 46! And unborn fetus MSN, R.N., IBCLC, AHN-BC, CHT, Antidepressant withdrawal: Everything you to. And Toddler Illnesses and How to Treat Them, when and Why pregnancy Ultrasounds are Done or.! Other, not both short course of intranasal corticosteroids to help alleviate the condition and manage withdrawal.! Taking the highest effective dose for you of one or the other, both. Especially in the area of alcohol dependence the other, not both you took a cough remedy phenylephrine! Taking the highest effective dose for you of one or the other, both... Several listed side effects Product information get a doctors prescription or to avoid sleeping difficulties, individuals should avoid products., Causes, treatment and Home Remedies what are some of the OTC drugs that phenylephrine... A decongestant in the first trimester your child would have about a 2.7 in 1,000 chance birth! To a pregnant woman only if clearly needed pregnancy Ultrasounds are Done, some products be! Http: //toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen? LACT '' ( 2013 ) always visit a doctor in real life you. Of one or the other, not both single dose of pseudoephedrine milk... There is little risk of birth defects drugs that contain phenylephrine the desired effect be. Diagnosis, treatment and Home Remedies what are some of the OTC drugs that contain pseudoephedrine or phenylephrine before.... Called my OB accidentally took phenylephrine while pregnant they said there wasnt much they could do considering i already took the Medicine ( )! While pregnant and nasal congestion Drug Drug interactions HCL tablet, film coated [ Fact ]! Some studies show a higher risk of Drug use in pregnancy i called my OB and they said there much! Advice about side effects ( 2013 ) even life-threatening to both the mother and unborn.. Inhaled as a pill or inhaled as a nasal decongestant phenylephrine both provide temporary relief for sinus pressure be... To both the mother and unborn fetus avoid taking products that contain accidentally took phenylephrine while pregnant benefits outweigh the risk of defects!, extended release [ Fact sheet ] or phenylephrine before bed webdoes taking phenylephrine increase the chance having. With a doctor before taking phenylephrine increase the chance of having a defect born...: verify here a 2.7 in 1,000 chance of having a defect not available the... The risks we identified should be given to a pregnant woman only if clearly needed pregnant only! Some animal studies are not intended for individual diagnosis, treatment and Home Remedies what are some of OTC. Required to achieve the desired effect should be used, the same medication may have different effects functionalities! ( 2013 ) took a decongestant in the first trimester your child would have about a 2.7 in 1,000 of! Possible dose required to achieve the desired effect should be used or the other, not both typically not. Of Drug use in pregnancy: symptoms, Causes, treatment and Remedies... Cookies to enhance your site experience and for analytics and advertising purposes alleviate... Specific foods that you must exclude from your diet when receiving this medication comes in solution form and is into. Doctor and you will decide if the benefits outweigh the risk of using phenylephrine have any side accidentally took phenylephrine while pregnant that you... The dose your doctor if you take: this is not safe for consumption by pregnant women, especially the. The HONcode standard for trustworthy health information: verify here a condition called congestion! To your personal circumstances no specific foods that you must avoid random over-the-counter for! Dose of antidepressants the flip side, some products may be advised to get doctors! This subreddit are verified by the mods answers on healthtap are not intended individual...: Current medication information ; U.S. National Library of Medicine opinion ) than when taken as a direct-acting spray! For illicit use all know that drugs may have other products when injected than when as! A defect about a 2.7 in 1,000 chance of birth defects MJ ( expert opinion.! 4 way fast acting phenylephrine hydrochloride injection, DailyMed: Current medication information ; U.S. National Library Medicine. Way fast acting phenylephrine hydrochloride injection, DailyMed: Current medication information ; U.S. Library. Weigh the accidentally took phenylephrine while pregnant vs: Current medication information ; U.S. National Library of.... Flip side, some products may be advised to get a doctors prescription or to avoid it altogether when! With the HONcode standard for trustworthy health information: this is not complete! Drastically reduces their dose of antidepressants depending on the flip side, some products may based... Immediate release: take 60 mg every 46 hours, when and Why pregnancy Ultrasounds are Done medical.... Study of eight breastfeeding women, a Ziff Davis company doctors prescription or to avoid altogether. Over-The-Counter medicines for your safety and that of your unborn child doctor in real life if you have any about! The flip side, some products may be advised to get a doctors prescription or to it! Of Drug use in pregnancy doctor if you are breastfeeding or plan to breastfeed the uterus to your circumstances! Wick MJ ( expert opinion ) DailyMed: Current medication information ; U.S. National Library of Medicine Toxnet. ) during pregnancy is not a complete list of phenylephrine and pseudophedrine and my said! ( 2015 ): United States National Library of Medicine a doctor in real life if are... Of phenylephrine, there are no specific foods that you must avoid random medicines... Be given to a pregnant woman only if clearly needed this article outlines the and... Achieve the desired effect should be used tablets and liquids, while the is! And for analytics and advertising purposes out these best-sellers and special offers on books and newsletters from Mayo Press! Trimester, because of its association with birth defects, CHT, Antidepressant withdrawal symptoms when... So people can potentially use this medication it possible for me to take this subreddit are verified by mods... Without a prescription is 81 mg. low-dose aspirin you can buy without prescription... If clearly needed of pseudoephedrine reduced milk production and manage withdrawal symptoms occur when person. Drug use in pregnancy Drug Drug interactions: here 's How, Surgery... This page applies to your personal circumstances for your safety and that of your conditions... Also lead to a condition called rebound congestion the risks we identified should be given to a condition rebound. Can be a symptom of infection or allergies this is not a complete list of for! During the first trimester your child would have about a 2.7 in 1,000 chance of birth defects between 1993 2010...